Oncology Hub

    Cancer, your cycle, and complementary care that works with your treatment

    Which cancers affect women across different communities, which modern treatments are genuinely moving outcomes, and which complementary approaches may help alongside them — with the interaction risks laid out plainly so you can raise them with your oncology team.

    Cancer Support Notice

    Symptom tracking is for personal reference only. Report any concerning symptoms to your oncology team immediately. This app does not replace medical care.

    Who this is for

    Anyone newly diagnosed, in active treatment, or living in survivorship — and the people supporting them. Nothing here diagnoses, treats, or replaces your care team. Complementary approaches are used alongside medical treatment, never instead of it, and every one needs clearing with your oncology team first because interactions are real.

    Step 1 — Cancer type

    Step 2 — Where you are

    Breast cancerin active treatment

    The most commonly diagnosed cancer in women worldwide, with outcomes that vary sharply by subtype and by how early it is found.

    Who it affects

    Risk rises with age, but incidence in women under 45 is climbing. Black women are diagnosed with triple-negative disease more often and face higher mortality at the same stage, largely reflecting access and delays rather than biology alone. Ashkenazi Jewish families carry higher BRCA prevalence.

    Modern treatments seeing success

    Targeted HER2 therapy

    Antibody and antibody-drug conjugate treatments aimed at HER2-positive disease.

    Turned one of the most aggressive subtypes into one of the most treatable over two decades.

    Endocrine therapy

    Tamoxifen and aromatase inhibitors, often for five to ten years, in hormone-receptor-positive disease.

    Long-term recurrence reduction is well established.

    CDK4/6 inhibitors

    Oral drugs added to endocrine therapy in advanced hormone-receptor-positive disease.

    Consistently extend the time before disease progresses.

    Immunotherapy for triple-negative disease

    Checkpoint inhibitors combined with chemotherapy in selected patients.

    Improved outcomes in a subtype that previously had few targeted options.

    Genomic recurrence testing

    Tumour gene assays that estimate benefit from chemotherapy.

    Lets many women safely avoid chemotherapy altogether.

    Cycle, hormonal, and menopause effects to expect

    • Chemotherapy commonly pauses or permanently ends periods, and the chance of permanence rises with age.
    • Tamoxifen can cause irregular bleeding, hot flashes, and heavier or lighter cycles; it does not reliably prevent pregnancy.
    • Aromatase inhibitors produce abrupt, often intense menopausal symptoms including joint pain and vaginal dryness.
    • Ovarian suppression injections cause a rapid, medically induced menopause.

    Complementary supports people ask about

    These sit alongside medical treatment, never in place of it. Confirm every one with your oncology team before starting — including anything you already take.

    Aerobic and resistance exercise

    Evidence: strong

    Among the best-supported supports for treatment-related fatigue, mood, and long-term outcomes.

    Confirm with your oncology team before starting.

    Acupuncture for hot flashes and joint pain

    Evidence: mixed

    Several trials show benefit for aromatase-inhibitor joint pain and vasomotor symptoms.

    Confirm with your oncology team before starting.

    Cognitive behavioural therapy for insomnia

    Evidence: strong

    Outperforms sleep medication for treatment-related insomnia in most studies.

    Confirm with your oncology team before starting.

    Mindfulness and breath-based practice

    Evidence: mixed

    Consistent signal for anxiety and distress, weaker for physical symptoms.

    Confirm with your oncology team before starting.

    Scalp cooling during chemotherapy

    Evidence: mixed

    Reduces hair loss for many regimens; availability varies by centre.

    Confirm with your oncology team before starting.

    Vitamin D and calcium for bone protection

    Evidence: mixed

    Often recommended alongside aromatase inhibitors — dosing is a clinical decision, not a self-serve one.

    Confirm with your oncology team before starting.

    Discuss before you take — possible interactions

    • Soy and concentrated phytoestrogen supplementsFood-level soy is generally considered fine; isolated high-dose isoflavone supplements are a separate question in hormone-receptor-positive disease.
    • Black cohosh and red cloverMarketed for hot flashes, but hormonal activity and liver effects are unresolved in breast cancer.
    • Some SSRIs with tamoxifenCertain antidepressants reduce conversion of tamoxifen into its active form; the choice of antidepressant matters.
    • St John's wortA strong enzyme inducer that can lower blood levels of many chemotherapy and targeted agents.
    • High-dose antioxidant supplementsVery high doses of vitamins C or E during chemotherapy or radiation are debated and may work against treatments that rely on oxidative damage.
    • Grapefruit and grapefruit juiceAlters how the liver clears several oral cancer drugs, changing exposure unpredictably.
    • Turmeric and curcumin extractsConcentrated extracts can affect drug metabolism and bleeding risk; culinary amounts are a different question from supplements.
    • Green tea extract (concentrated)High-dose extracts have been associated with liver strain and may interact with some agents.
    • Ginkgo, high-dose fish oil, and vitamin ECan increase bleeding risk, which matters around surgery and when platelets are low.

    What to focus on right now

    • Track symptoms daily — patterns are more useful to your team than single bad days.
    • Report new or worsening symptoms rather than waiting for the next scheduled visit.
    • Clear any new supplement, tea, or herbal product with your oncology team first.
    • Gentle, regular movement is better tolerated than occasional intense sessions.
    • Protein and hydration matter more during treatment than any specific diet trend.

    Questions for my oncology team

    1. 1.Which side effects am I likely to get in the next cycle, and when do they peak?
    2. 2.Is this complementary approach safe alongside my current regimen?
    3. 3.What can I take for nausea, fatigue, or neuropathy that will not interfere?
    4. 4.Should I expect my periods to stop, and is that permanent?
    5. 5.What warning signs mean I should call you or go to the emergency department?
    6. 6.Here is everything I take, including supplements and teas — is anything a problem with my treatment?

    Cancer types covered in this hub

    Breast cancer

    The most commonly diagnosed cancer in women worldwide, with outcomes that vary sharply by subtype and by how early it is found.

    Treatments covered: Targeted HER2 therapy, Endocrine therapy, CDK4/6 inhibitors, Immunotherapy for triple-negative disease, Genomic recurrence testing.

    Ovarian cancer

    Often found late because early symptoms are vague — bloating, fullness, urinary urgency, pelvic discomfort that persists.

    Treatments covered: PARP inhibitors, Cytoreductive surgery with platinum chemotherapy, Anti-angiogenic therapy, Germline and somatic genetic testing.

    Cervical cancer

    Largely preventable through HPV vaccination and screening, yet still one of the leading causes of cancer death in women where access is limited.

    Treatments covered: Chemoradiation, Immunotherapy, Fertility-sparing surgery, HPV vaccination and self-sampling screening.

    Endometrial (uterine) cancer

    One of the few cancers with rising incidence, closely linked to metabolic health. Abnormal bleeding — especially after menopause — is the key early signal.

    Treatments covered: Molecular classification, Immunotherapy for mismatch-repair-deficient disease, Minimally invasive and sentinel node surgery, Progestin therapy for fertility preservation.

    Colorectal cancer

    Incidence in adults under 50 has risen steadily, which is why screening ages have been lowered in several countries.

    Treatments covered: Immunotherapy for MSI-high tumours, Total neoadjuvant therapy for rectal cancer, Circulating tumour DNA monitoring, Targeted therapy by mutation profile.

    Thyroid cancer

    Diagnosed three times more often in women than men, usually with excellent long-term outcomes — which has shifted the conversation toward avoiding overtreatment.

    Treatments covered: Active surveillance for low-risk microcarcinoma, Lobectomy instead of total thyroidectomy, Targeted therapy for advanced disease, Selective radioactive iodine use.

    Lymphoma and blood cancers

    A group of cancers that often affect younger adults, where treatment intensity makes fertility and long-term effects central conversations from day one.

    Treatments covered: CAR-T cell therapy, Bispecific antibodies, Antibody-drug conjugates, Response-adapted therapy.

    Another cancer type

    General principles that apply across cancer types when your specific diagnosis is not listed here.

    Treatments covered: Biomarker-driven treatment, Immunotherapy, De-escalation strategies, Clinical trials.

    Read deeper

    Long-form guides on treatment, complementary care, and life after cancer.

    Common questions

    Can natural remedies replace cancer treatment?

    No. Complementary approaches are used alongside medical treatment to help with symptoms and quality of life. Replacing evidence-based cancer treatment with alternative approaches is associated with worse survival. Everything on this page assumes you are also receiving oncology care.

    Which supplements are risky during chemotherapy?

    St John's wort, high-dose antioxidant vitamins, concentrated turmeric or green tea extracts, grapefruit, and immune-stimulating supplements are the most commonly flagged. The safest approach is to bring every product you take, in its packaging, to your oncology team before starting treatment.

    Will cancer treatment stop my periods permanently?

    It depends on the treatment and your age. Alkylating chemotherapy and pelvic radiation carry the highest risk of permanent ovarian failure, and risk rises with age at treatment. Many younger women see periods return months after treatment ends. Ask your team directly rather than assuming either outcome.

    Should I ask about fertility preservation before treatment?

    Yes, and as early as possible. Egg or embryo freezing and ovarian suppression usually need to happen before treatment starts, and the window is often only a few weeks. Ask at your first oncology appointment, even if you are unsure about future pregnancy.

    Is exercise safe during cancer treatment?

    For most people, yes, and it is one of the best-supported ways to reduce treatment-related fatigue. Intensity and type should be adjusted for blood counts, surgical recovery, bone involvement, and neuropathy, so confirm the plan with your care team.

    Track symptoms and side effects, free

    Log fatigue, pain, nausea, and cycle changes day by day, and bring the pattern — not a guess — to your next oncology appointment.

    Start tracking free

    PERIODiQ provides health tracking and educational content only. It is not intended to diagnose, treat, cure, or prevent any disease. Always seek the advice of your physician or qualified healthcare provider with questions regarding a medical condition.